Table 2.

Quantitation of Neuronal Golgi Fragmentation (GOLGI) and Stathmin Accumulation (STATH)

	STATH	±SEM	GOLGI	±SEM
60 to 90 days	0.7	0.33	2.2	0.17
End stage	2.8	0.17	0.7	0.21

Scoring was done on one cross-section of spinal cord from each animal expressing SOD1^G93A. In paralyzed mice animals very few motor neurons were left; this affected the low score for the Golgi apparatus, which was scored only in the cell body and not in the processes as Stathmin. 

Stathmin scoring: 0, Rare golgi-like stain (same as in normal or WT/hSOD mice); 0.5, occasional grains; 1, some stain in a cell body and an occasional process; 2, intense stain in a cell body and a few processes; 3, more than 50 processes stained per field, one or more cell bodies with intense stain. 

Golgi apparatus (GA) scoring: 1, 1 to 2 cells with fragmented GA; 2, 3 to 5 cells with fragmented GA; 3, more than five cells with fragmented GA.