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. 2004 Nov;165(5):1781–1787. doi: 10.1016/S0002-9440(10)63433-5

Figure 5.

Figure 5

Expression of CEACAM1 and integrin β3 in MEL6 cells enhances invasion. A: MEL6 cells or MEL6 cells transfected either with cDNA for CEACAM1 or for integrin β3 were studied using the Matrigel invasion assay as described in Figure 1. B: Invasion of CEACAM1 transfected MEL6 cells in the absence (RPMI) or presence of anti-CEACAM1 inhibitors (0.2 μmol/L 4D1C2 and 0.2 μmol/L 12-140-4). C: Invasion of integrin β3 transfected MEL6 cells in the absence (RPMI) and presence of anti-CEACAM1 inhibitors (0.2 μmol/L 4D1C2 and 0.2 μmol/L 12-140-4). The data are means ± SD of five separate experiments. The mean invasion of untransfected MEL6 cells was assigned a value of 1.