Table 4.
No. of group | Treatment | Microdissected lesions | GST-P | No. of dysregulated genes*
|
|
---|---|---|---|---|---|
Up | Down | ||||
Experiment 1 | |||||
1 | NDEN+ clofibrate | Hepatocellular altered foci† | Positive | 279 | 67 |
2 | NDEN+ Wy-14,643 | Hepatocellular altered foci‡ | Negative | 67 | 7 |
3 | NDEN alone | Hepatocellular altered foci† | Positive | 137 | 71 |
Experiment 2 | |||||
1 | NDEN+ clofibrate | Hepatocellular altered foci‡ | Negative | 110 | 51 |
Number of dysregulated genes in the lesion as compared to adjacent normal tissue.
Clear cell foci.
Amphophilic cell foci.