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MMP-2 cleaved galectin-3 displays greater affinity for endothelial cells. HUVECs were incubated with indicated amounts of radioiodinated full-length or MMP-2-cleaved recombinant galectin-3 protein in the absence or presence of 50 mmol/L lactose. A and B: Full-length galectin-3 in the absence (A) or presence (B) of lactose. C and D: Cleaved galectin-3 in the absence (C) or presence (D) of lactose.
