Table 2.
PrP-res Distribution in the Brain of tgGFAP Mice
| Days after infection | 84 | 112 | 140 | 200 | 252 | 355 |
|---|---|---|---|---|---|---|
| Visual projection regions | ||||||
| Retina | − | − | +* | + | ++ | +++ |
| Lateral geniculate nucleus | − | − | + | + | + | ++ |
| Superior colliculus | − | − | − | − | − | − |
| Visual cortex (occipital) | − | − | − | − | − | + |
| Other brain regions | ||||||
| Neocortex (frontal/parietal) | − | − | − | + | ++ | +++ |
| Hippocampus | − | − | − | + | ++ | +++ |
| Cerebellum (deep cerebellar nuclei) | − | − | − | − | − | − |
| Cerebellum (granule cell layer) | − | − | − | + | ++ | +++ |
Indicates the intensity of PrP-res staining in that region.