Effect of indomethacin and nimesulide on GFAP levels in Tg2576 brains. A: Representative immunoblots of GFAP and β-actin levels in total cerebral cortex and hippocampus homogenates of Tg2576 on placebo (Con), indomethacin (Ind), or nimesulide (Nim). B: Semiquantitative measurement of GFAP/β-actin ratio in the same experiments (*, P < 0.01, n = 5 per group; age, 15 months old).