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Lack of effect of indomethacin and nimesulide on APP metabolism. Representative gels (A) and semiquantitative analyses (B) of total APP levels; full length-APP levels; secreted APPβ levels in total cerebral cortex and hippocampus homogenates from Tg2576 receiving placebo (Co), indomethacin (In), or nimesulide (Nim). Results of B are mean ± SEM; n = 5 per group; age, 15 months old.
