Skip to main content
. 2004 Dec;165(6):2033–2043. doi: 10.1016/s0002-9440(10)63254-3

Figure 6.

Figure 6

AGE-induced expression of TGF-β1 and CTGF mRNA in the primary cultures of rat MCs. TGF-β1 and CTGF mRNA expressions were measured by RT-PCR, as described in Material and Methods, and representative gel profiles are given in A and D. Summarized results for the time-course and dose-effect of AGE-induced TGF-β1 mRNA expression (B, C) and CTGF mRNA expression (E, F) are presented. For the time-course study, MCs were treated with 100 μg/ml of AGE-BSA for the indicated times and for the dose-response study, MCs were treated with AGE-BSA at the indicated doses for 48 hours. *, P < 0.05 versus control.