Figure 3.

Time course of the expression of tyrosinase mRNA transcripts in human epidermis after UVB irradiation. Epidermal sheets after UVB exposure were obtained by suction blister biopsy, as detailed in Materials and Methods, followed by real-time quantitative RT-PCR analysis of tyrosinase mRNA transcripts. The expression of tyrosinase transcripts in UVB-exposed epidermis was normalized against the expression of GAPDH. The values reported represent means ± SD from two to eight volunteers. Symbols for circles, triangles, and squares correspond to each volunteer. White isosceles triangles represent the average of volunteers. *, P < 0.05.