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UVB irradiation increases the production of ET-1 in human epidermis as revealed by immunohistochemistry. A: Immunostaining of nonexposed human epidermis with anti-ET-1. B: Immunostaining of nonexposed human epidermis with nonspecific IgG. C: Immunostaining of UVB-exposed human epidermis with anti-ET-1. D: Immunostaining of UVB-exposed human epidermis with nonspecific IgG. Scale bars, 70 μm.
