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The nicotinamide binding site and selected hydrogen bonds. Conventional hydrogen bonds are shown as blue dashed lines, C–HO interactions by green dashed lines. 2′ and 3′ identify the hydroxyl groups of the nicotinamide ribose and 2, 4, 6 the C atoms of the pyridine moiety. Leu159 is placed below the cofactor ribose and for reasons of clarity is not labelled.
