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. 2006 Oct 10;7:76. doi: 10.1186/1471-2350-7-76

Table 2.

Prevalence of APOA5 gene variants -1131T>C and S19W in Asian Indians and UK white subjects.

SNP -1131T>C S19W

TT TC CC Carrier* Frequency (95% CIs) Less common allele Frequency (95% CIs) SS SW WW Carrier* Frequency (95% CIs) Less common allele Frequency (95% CIs)
Pune Indians (n = 524) 336 170 18 0.36 (0.32–0.40) 0.20 (0.17–0.22) 497 27 0 0.05 (0.03–0.07) 0.03 (0.02–0.04)
UK whites (n = 237) 218 19 0 0.08 (0.05–0.11) 0.04 (0.02–0.06) 210 26 1 0.11 (0.07–0.15) 0.06 (0.04–0.08)
P value <0.00001 0.0015

Asian Indians (adults from the Pune Children Study) and UK white subjects (adults from the Plymouth EarlyBird study).

P values are calculated for differences in genotype frequencies between Pune Indians and UK white subjects. *Carrier frequency indicates individuals carrying at least one copy of the less common allele at either polymorphism. Neither population showed any deviation from HWE for either polymorphism (p > 0.05).