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. Author manuscript; available in PMC: 2007 Jul 1.
Published in final edited form as: Epilepsy Res. 2006 Mar 20;70(1):3–14. doi: 10.1016/j.eplepsyres.2006.02.002

Figure 5.

Figure 5

Blockade of caspase 8 reduces seizure-induced cell death. Cells were incubated with the caspase 8 inhibitor Ac-IETD-CHO or caspase 9 inhibitor Ac-LEHD-CHO (both 10 μM) for 10 min prior to seizure, and then for 24 hours following 40 min seizure. Cell death was assessed by LDH release assay. Data shown are mean ± sem (n= 4), * denotes P<0.01 vs. effect of seizure (Dunnet's post hoc test), ** denotes P<0.01 vs. non-seized control.