. 2006 Jun 1;2006(4):24396. doi: 10.1155/MI/2006/24396

Table 2.

Effect of ibuprofen and its NOE on the granulation tissues of 10-day-old dead space wounds (by Scheffes test—SPSS computer package). (OHP = orthohydroxyproline, GSH = reduced glutathione, TBARS = thiobarbituric acid reactive species, n = number of animals). The difference between any two means is statistically significant if the mean difference is more than the allowance value calculated.

Group (n)	Dose	Granulation breaking	Dry granulation	OHP	GSH	TBARS
Group (n)	(mg/kg)	strength(g)	weight (g)	mg/g	(μg/g)	(μM/g)

Control (8)	—	271 ± 15.5	32.6 ± 3	27.5 ± 2.2	7.08 ± 1.30	3.98 ± 0.60
Ibuprofen (7)	200	157 ± 9.9^a	16.3 ± 2.1	13.3 ± 2.4^a	34.87 ± 5.44^a	11.24 ± 1.40^a
NOE-Ibu (7)	300	403 ± 12.4^a, ^b	65.4 ± 6.5^a, ^b	43.4 ± 3.2^a, ^b	45.20 ± 4.30^a, ^b	2.25 ± 0.20^a, ^b

a = P < .05 versus control.

b = P < .05 versus ibuprofen.