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STZ-diabetes and HO-1 levels following EIU. Rats were treated ip with vehicle saline; LPS alone (nondiabetic); LPS+STZ (diabetic), or hemin (50 mg/kg 1 h prior to LPS or LPS+STZ). Significance is expressed as •P < .05 versus vehicle saline nondiabetic rats; * P < .05 and ** P < .01 versus LPS nondiabetic rats; ° P < .05 and °° P < .01 versus LPS+hemin nondiabetic rats.
