Table 1.
Experimental groups | Measures | |
Nondiabetic rats | Diabetic rats (streptozotocin, 70 mg/kg ip) | In each group the levels of the following parameters were measured: HO-1, MPO, IL-1beta, CXCL8 |
Vehicle (saline, 0.1 mL) | Vehicle (saline, 0.1 mL) | |
Vehicle + LPS (200 μg in 0.1 mL) | Vehicle + LPS (200 μg in 0.1 mL) | |
Hemin (50 mg/Kg ip in 0.1 mL, 1 h prior to LPS) | Hemin (50 mg/Kg ip in 0.1 mL, 1 h prior to LPS) | |
Zn-PP (50 μg/Kg ip, 6 h before hemin)+LPS | Zn-PP (50 μg/Kg ip in 0.1 mL, 6 h before hemin)+LPS |