Table 1.
Interactions of P450eryF with androstenedione and 9-aminophenanthrene
| Andro1 | 3A4 | Andro2 | 3A4 | PAH1 | 3A4 | PAH2 | 3A4 |
|---|---|---|---|---|---|---|---|
| Asn-89 | Ala-117 | Ala-74 | — | Gly-91 | Ser-119 | Ala-74 | — |
| Gly-91 | Ser-119 | Tyr-75 | Thr-103 | Val-237 | Ile-301 | Phe-78 | Arg-106 |
| Thr-92 | Ile-120 | Phe-86 | Met-114 | Ala-241 | Ala-305 | Phe-86 | Met-114 |
| Ala-241 | Ala-305 | Ser-171 | Leu-211 | Pro-288 | Ala-370 | Val-237 | Ile-301 |
| Glu-244 | Glu-308 | Ile-174 | Asp-214 | Leu-392 | Gly-480 | Ala-241 | Ala-305 |
| Ala-245 | Thr-309 | Leu-175 | Phe-215 | Leu-391 | Leu-479 | ||
| Glu-288 | Met-371 | Leu-240 | Phe-304 | ||||
| Leu-392 | Gly-480 | Ala-241 | Ala-305 | ||||
| Wat-746 | — | Glu-244 | Glu-308 | ||||
| Leu-391 | Leu-479 |
Homologous residues of P4503A4 are given.