Table 1a.

Skin histopathological characteristics of the skin related to metastasis (n = 110)

		n	%META'S	X2L	P	OR	Lower	Upper	n
Grading	1	41	51			2.48	1.03	5.94
	2	41	51			2.48	1.03	5.94
	3	22	86			14.93	3.8	58.68
Clark*	1	19	0	51.38	<0.001	–	–	–
	2	11	9			5.57	0.21	149.16
3	28	46			33.95	1.87	617.08
4	27	70			89.48	4.83	1659.05
5	21	86			206.23	9.95	4268.42
RClark	1 + 2 + 3	58	24	32.65	<0.001	–	–	–	106
	4	27	70			7.46	2.69	20.74
	5	21	86			18.86	4.83	73.63
Max diam	≤15	51	24	26.97	<0.001	9.25	3.74	22.85	101
	>15	50	74
Breslow	≤2.85	45	13	42.90	<0.001	25.28	8.17	78.20	89
	>2.85	44	80
Perineural invasion	0	64	45	14.97	<0.001	8.851	2.41	32.57	89
	1	25	88
Angio-invasion	0	62	42	22.89	<0.001	17.31	3.76	79.62	89
	1	27	93
Lymphocytes	0	95	53	6.98	0.01	0.16	0.34	0.78	108
	1	13	15
Histiocytes	0	76	46	0.45	0.50	1.33	0.58	3.04	108
	1	32	53
Eosinophils	0	82	42	6.2	0.013	3.18	1.24	8.15	108
	1	26	69
Neutrophils	0	102	49	0.57	0.45	0.52	0.91	2.97	108
	1	6	33
Plasma cells	0	75	39	9.00	0.003	3.65	1.52	8.76	108
	1	33	70
Infiltration	0	96	52	5.84	0.16	0.16	0.04	0.89	108
	1	12	17
Ulceration	0	87	43	2.83	0.09	2.48	0.84	7.31	104
	1	17	65
Desmoplasia	0	66	21	47.09	<0.001	29.71	8.99	98.19	102
	1	36	89
Margins	1	85	53	3.76	0.15	–	–	–	109
	2	15	40			0.59	0.19	1.81
	3	9	22			0.25	0.05	1.29

^*½ added to frequencies.

OR + odds ratio.

log likelihood χ².

%META'S, %metastasis.