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Proinflammatory response of THP-1 cells to N. meningitidis. The magnitude of TNF release in response to live wild-type (wt) N. meningitidis and mutants with truncated LOS (galE), without capsule (siaD), or without capsule together with truncated LOS (cps) was measured by ELISA. Each bar represents the median and interquartile range of three separate experiments. P > 0.05 (Kruskal-Wallis test).
