Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Numbers of mice per group (n = 5) that developed necrosis by days 7 and 14
| Infective dosea | No. of mice that developed necrosis after infection with:
|
||||
|---|---|---|---|---|---|
| Day post- infection | Wild-type M5 GAS | sloΔ1 mutant | sagBΔ1 mutant | sloΔ1 sagBΔ1 mutant | |
| ∼3 × 107 | 7 | 4 | 5 | 5 | 4 |
| 14 | 5 | 5 | 5 | 5 | |
| ∼3 × 106 | 7 | 3 | 5 | 3 | 0 |
| 14 | 5 | 5 | 3 | 1 | |
| ∼3 × 105 | 7 | 1 | 0 | 0 | 0 |
| 14 | 1 | 2 | 0 | 0 | |
At higher infective doses, all mice developed necrosis by day 7.
