TABLE 2.
Activated-T-cell phenotypesa
| Antigen expression | Mean % activated T cells ± SD in:
|
|||
|---|---|---|---|---|
| Mesenteric lymph nodes
|
Spleens
|
|||
| Clinically healthy animals | Animals with chronic diarrhea | Clinically healthy animals | Animals with chronic diarrhea | |
| CD4+ | ||||
| CD45RA+ CD69− | 48.5 ± 8.2 | 24.1 ± 7.1 | 42.3 ± 2.8 | 24.7 ± 7.3 |
| CD45RA− CD69+ | 12.3 ± 4.0 | 23.3 ± 4.0b | 12.6 ± 4.3 | 24.0 ± 9.8 |
| CD45RA+ CD69+ | 5.1 ± 0.7 | 5.2 ± 2.4 | 5.9 ± 1.7 | 8.9 ± 3.7 |
| CD8+ | ||||
| CD45RA+ CD69− | 77.7 ± 8.9 | 50.7 ± 4.4 | 52.6 ± 9.3 | 33.5 ± 9.9 |
| CD45RA− CD69+ | 4.7 ± 2.6 | 13.9 ± 5.3 | 11.3 ± 5.2 | 10.8 ± 5.9 |
| CD45RA+ CD69+ | 5.6 ± 1.0 | 9.8 ± 4.2 | 19.3 ± 2.8 | 43.5 ± 10.9 |
a
Values represent subsets of animals with chronic diarrhea (n = 3) and clinically healthy controls (n = 3).
b
A statistically significant difference (P < 0.05) between the two groups is indicated.