Table 1.
Relationship of TADs and degrons in unstable transcription factors
| Factor | Position of TAD* | Position of degron* | References† |
|---|---|---|---|
| E2F-1 | 368–437 | 418–437 | (15) |
| (4) | |||
| Fos | 308–380 | 359–380 | (22) |
| (23) | |||
| GCN4 | 87–152 | 99–106 | (24) |
| (25) | |||
| HIF-1α | 531–575 | 401–603 | (26) |
| (27) | |||
| Jun | 5–196 | 1–67 | (28) |
| (2) | |||
| Myc | 1–146 | 1–143 | (29) |
| (1) | |||
| p53 | 1–73 | 1–40 | (30) |
| (31) | |||
| Rel | 416–521 | 427–480 | (32) |
| (33) | |||
| β-catenin | 695–781 | 32–37 | (34) |
| (35) | |||
| Myb | 198–356 | 549–536 | (36) |
| (37) |
*
In cases where two or more TADs or degrons have been mapped within a single transcription factor, only the overlapping TADs and degrons are listed.
†References are listed for the activation domain first, degron second.