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. Author manuscript; available in PMC: 2006 Oct 27.
Published in final edited form as: Chem Biol Interact. 2006 Apr 4;163(1-2):54–67. doi: 10.1016/j.cbi.2006.03.001

Table 1.

Mitochondrial anion transporters

Carrier Function Charge Transfer Inhibitors
Adenine nucleotide translocase (AAC1–3; Slc25a4–6) ADP3− in, ATP4− out Electrogenic Atractyloside, Carboxyatractyloside Bongkrekic acid
Phosphate (PiC; Slc25a3) H2PO4− in, OH− out Electroneutral SH-reagents
Dicarboxylate (DIC; Slc25a10) Malate2− in, HPO42− out Electroneutral Butylmalonate
2-Oxoglutarate (OGC; Slc25a11) 2-Oxoglutarate2− in, malate2− out Electroneutral Phenylsuccinate
Glutamate–Aspartate Glutamate− + H+ in, Electrogenic —
(AGC1/2; Slc25a12/13) Aspartate− out
Glutamate–Hydroxide (GC1/2; Slc25a22/18) Glutamate− in, OH− out Electroneutral —
Tricarboxylate / Citrate (CIC; Slc25a1) Citrate3− + H+ in, malate2− out Electroneutral 1,2,3-Benzenetricarboxylate, triethyl citrate
Monocarboxylate(MCC) Pyruvate− in, OH− out Electroneutral Cyanohydroxycinnamate