Figure 6.

Effects of thalidomide treatment alone for 7 days (thal), as compared to daily thalidomide treatment after the TNBS/ethanol enema (TNBS+thal), on (A) endothelial cell-leukocyte interaction, (B) perfusion index, (C) red blood cell velocity (RBCV) and (D) functional capillary density (FCD) in the mucosa of the descending colon (n=3 for each group with 10 randomly chosen regions analysed per animal; ^*P<0.05 vs thalidomide). Note that due to the larger size of the venules analysed in these animals, the absolute number of leukocytes sticking to the endothelium as well as absolute RBCV differ from the values shown in Figure 3.