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Inhibition of the hydrolysis by rat brain membranes of 2 μM [3H]-AEA by a series of palmitoylethanolamide homologues (a) C16:0–C3:0 (b) C16:0–C18:0 and C18:1. Shown are means of 3–6 experiments, with no preincubation with the compounds and membranes prior to addition of [3H]-AEA. The data for palmitoylethanolamide are the same in both graphs.
