Figure 1.

Plasma concentrations of ACTH and corticosterone after acute administration of diazepam (10 mg kg⁻¹ i.p.) or rolipram (0.2 mg kg⁻¹ i.p.). Control animals were injected with the respective vehicle. Testing occurred 30 or 20 min after diazepam or rolipram injections respectively. Values are the mean±s.e.mean of at least five experiments. Significance was determined by one-way ANOVA followed by the Student-Newman-Keuls test. ^***P<0.001 vs control; ^**P<0.01 vs control.