Table 3.
Outcome | Antiplatelet drug(s) prescribed | No. (%) with outcome | Crude OR (95% CI) | Adjusted OR (95% CI)** |
Excessive transfusion* | Neither | 260 (52.4) | 1.0 | 1.0 |
Aspirin alone | 58 (55.8) | 1.1 (0.8–1.8) | 1.0 (0.6–1.6) | |
Clopidogrel alone | 6 (54.6) | 1.1 (0.3–3.6) | 0.7 (0.2–2.5) | |
Aspirin and clopidogrel | 33 (71.7) | 2.3 (1.2–4.5) | 2.2 (1.1–4.3) | |
Any transfusion | Neither | 300 (60.5) | 1.0 | 1.0 |
Aspirin alone | 70 (66.7) | 1.3 (0.8–2.0) | 1.1 (0.7–1.7) | |
Clopidogrel alone | 9 (81.8) | 3.0 (0.6–13.8) | 1.8 (0.4–9.2) | |
Aspirin and clopidogrel | 36 (78.3) | 2.4 (1.2–4.9) | 2.1 (1.0–4.5) |
* Defined as a transfusion of ≥ 2 units of non-autologous packed red blood cells, ≥ 2 units of fresh frozen plasma, ≥ 5 units of cryoprecipitate, or ≥ 5 units of platelets, during CABG and up to the second post-operative day. ** Adjusted for age, sex and receipt of 1 or more units of autologous whole blood perioperatively. OR odds ratio; CI confidence interval