FIG. 6.

Architecture of actin fibers in the labyrinth layer and cultured trophoblasts from the placentas of wild-type (ROCK-II^+/+) and ROCK-II^−/− mice. (A) Cytoarchitecture of actin fibers in the labyrinth layer of wild-type and ROCK-II^−/− placentas. (B and C) Actin structures in clusters of cultured trophoblasts from wild-type (B) and ROCK-II^−/− (C) placentas. Cells were cultured in the absence or presence of 10 μM Y-27632. Note that the structure of actin bundles is not different in the wild-type and ROCK-II^−/− cells, and the structures of the actin bundles in the wild-type and ROCK-II^−/− cells treated with Y-27632 were similar. Bars, 20 μm (A) and 50 μm (B and C).