Table 1. Global helical parameters of duplexes with five-membered sugars.
DNA type | Average helical twist (°) | Average helical rise per residue (Å) | No. of nucleotides per helix | Base pair inclination (°) | x-displacement (Å) |
---|---|---|---|---|---|
Right-handed helix | |||||
Da | 45.0 | 3.02 | 8.0 | –15.9 | 1.05 |
Cb | 39.5 | 3.31 | 8.5 | –17.0 | 3.45 |
α-DNA:β-DNAc | 39.8 | 3.37 | 10.1 | –3.1 | –1.16 |
Bd | 36.1 | 3.37 | 10.0 | 2.4 | 0.80 |
RNA:DNA duplexe | 32.7 | 2.62 | 11.0 | 11.7 | –4.46 |
Ad | 31.1 | 2.90 | 11.5 | 12.0 | 4.10 |
Left-handed helix | |||||
Zd | –30.0 | 3.8 | 12.0 | –6.2 | 3.3 |
bCurves calculation on C-DNA model (BII_9_1_model.pdb from http://www.fos.su.se/physical/lorens/) (9).
cα-/β-DNA: Curves calculation on the reconstructed model (11).
dValues from Eschenmoser and Dobler (4).
eCurves calculation on the structure of the RNA:DNA duplex, pdb entry 124D (6).