Table 4. x-component (in Å), ϖ and χ (in °) angle of the denoted vector for different nucleic acid analogs as depicted in Figure 9.
Vector | x-component | ϖ | χ | |
---|---|---|---|---|
B-DNA | C5′–O3′ | –2.2 | 309 | 262 |
A-RNA | C5′–O3′ | –0.8 | 318 | 194 |
HNA | C6′–O4′ | –0.6 (-0.7)a | 307 (316)a | 215 (223)a |
p-RNA | C4′–O2′ | 2.7 (3.0)b | 312 (296)b | 241 (230)b |
O4′–O3′ | 0.2 | 350 | 241 | |
α-Lyxo | C4′–O2′ | 2.2 | 18 | 212 |
O4′–O3′ | –0.6 | 344 | 212 | |
α-DNA | C5′–O3′ | 3.0 | 111 | 140 |
Parallel: O3′–C5′ | –3.0 | 291 | 140 | |
α-Homo-DNA | C6′–O4′ | 0.3 | 116 | 136 |
Parallel: O4′–C6′ | –0.3 (–0.3)c | 296 (326)c | 136 (158)c | |
β-Homo-DNA | C6′–O4′ | –1.6 (–1.6)d | 281 (233)d | 230 (278)d |
Values are listed for energy-minimized monomers and as measured in a duplex structure if available. For comparison, values in an A-RNA and B-DNA canonical duplex are mentioned.
a pdb entry 1EJZ (18).
bQuasi-linear model reconstructed from Schlonvogt et al. (23).
cModel from Froeyen et al. (13).
dLinear model reconstructed from Otting et al. (14).