Table 2. Torsion angles of bridged nucleosides.
Type | Bridged nucleoside | δ angle | Average δ angle |
---|---|---|---|
2′,4′-BNA/LNA | 2′-O,4′-C-methylene adenosine | 62.5° | 66° |
2′-O,4′-C-methylene thymidine | 68.5°, 66.9° | ||
2′-O,4′-C-methylene uridine | 66.2° | ||
ENA | 2′-O,4′-C-ethylene adenosine | 75.7° | 77° |
2′-O,4′-C-ethylene-N2-isobutyrylguanosine | 78.9° |