Table 2.
Comparison of the current national service framework for coronary heart disease cholesterol screening criteria, the Sheffield tables, age thresholds, and estimated risk assessments. Values are percentages (95% confidence intervals) unless stated otherwise
| Strategy to identify people for cholesterol measurement | Adults (aged 30-74 years with no previous history of MI, stroke, angina) identified for cholesterol measurement | People at ≥ 15% risk identified | No of cholesterol measurements needed to identify one person at ≥ 15% risk (yield) |
|---|---|---|---|
| National service framework criteria | 43.4 (42.2 to 44.6) | 81.2 (80.2 to 82.2) | 3.2 |
| Sheffield tables | 73.1 (72.0 to 74.2) | 99.91 (99.83 to 99.99) | 4.4 |
| All people aged ≥50 years | 46.3 (45.1 to 47.5) | 92.8 (92.1 to 93.4) | 2.9 |
| All people whose estimated risk calculated by using fixed TC:HDL (5.3 in men and 4.6 in women) is ≥15% | 17.8 (16.8 to 18.7) | 75.9 (74.8 to 76.9) | 1.4 |
| National service framework criteria plus Sheffield tables | 78.4 (77.4 to 79.4) | 99.91 (99.83 to 99.99) | 4.7 |
| National service framework criteria plus all those ≥50 years | 60.9 (59.8 to 62.2) | 97.5 (97.2 to 97.9) | 3.7 |
| National service framework criteria plus all those whose estimated risk calculated by using fixed TC:HDL is ≥15% | 46.8 (45.5 to 48.0) | 93.4 (92.7 to 93.9) | 3.0 |
MI=myocardial infarction; TC:HDL=ratio of total cholesterol to high density lipoprotein cholesterol.