Table 6.
Percentage reduction (95% confidence interval) in risk of ischaemic heart disease events in randomised trials (excluding first two years of treatment) compared with expected reductions from cohort study data6
|
Reduction in risk of IHD events
|
||||
|---|---|---|---|---|
| Serum cholesterol reduction (mmol/l) | Mean reduction (mmol/l) | Total no of events | Observed in trial data | Expected from cohort study data* |
| 0.2 | 0.5 | 2311 | 20 (7 to 31) | 23 (20 to 26) |
| 0.8 | 1.0 | 3556 | 32 (27 to 36) | 41 (37 to 45) |
| ≥1.5 | 1.6 | 705 | 51 (42 to 58) | 57 (52 to 61) |
*
At age 60 years (average age at which ischaemic heart disease events occurred).