Table 4.

Efficacy: blood pressure lowering effects of drugs when used at half standard dose separately and in combination

	Blood pressure reduction* (95% CI)
	One drug	Two drugs	Three drugs
Systolic blood pressure (mm Hg)	6.7 (6.1 to 7.2)	13.3 (12.4 to 14.1)	19.9 (18.5 to 21.3)
Diastolic blood pressure (mm Hg)	3.7 (3.1 to 4.3)	7.3 (6.2 to 8.3)	10.7 (9.1 to 12.4)

^*Reductions in blood pressure adjusted to a usual pretreatment blood pressure of 150/90 mm Hg, the average blood pressure in people aged 50-69 years who have a stroke or ischaemic heart disease event.⁷