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. 2003 Jun 28;326(7404):1427. doi: 10.1136/bmj.326.7404.1427

Table 7.

Effects of blood pressure lowering drugs on reducing the incidence of stroke and ischaemic heart disease events when used separately and in combination at half standard dose*

Percentage (95% CI) reduction in incidence
Disease One drug Two drugs Three drugs
Stroke 29 (26 to 31) 49 (42 to 55) 63 (55 to 70)
Ischaemic heart disease events 19 (17 to 21) 34 (29 to 40) 46 (39 to 53)
*

Calculated from reductions in blood pressure in table 4 and estimates of association between blood pressure and disease events at age 60-69 years from the Prospective Studies Collaboration.1