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. 2006 Sep 27;103(41):15218–15223. doi: 10.1073/pnas.0607131103

Fig. 5.

Fig. 5.

Partial block of feed-forward inhibition rescues LTP in the presence of Zn2+ chelator. (A) AP-EPSP pairing-induced LTP of the EPSP in the LA neuron in the presence of 100 μM PTX. Traces in Upper are the cortico-amygdala EPSPs recorded before (trace 1) and after (trace 2) LTP induction (arrow). (B) Summary graph of the LTP experiments as in A (n = 6). (C) LTP of the EPSPs in the presence of 1 μM PTX and TPEN (100 nM). Traces show EPSPs recorded before (trace 1) and after (trace 2) the pairing procedure. (D) Summary graph of the LTP experiments as in C (n = 6). (E) The effect of different concentrations of PTX on isolated monosynaptic GABAAR IPSC (n = 4). Traces in Upper show that the IPSC was completely blocked by 100 μM PTX. (F) Summary of LTP experiments. Error bars indicate SEM.