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. 2006 Oct 6;103(42):15657–15662. doi: 10.1073/pnas.0604621103

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© 2006 by The National Academy of Sciences of the USA

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Fig. 4. — The distal C terminus of Cav1.4 suppresses CDI in Cav1.2. (A) Schematic representation of Cav1.2-1.4 chimeric channels. Channel portions derived from Cav1.2 and Cav1.4 are displayed in red and black, representatively. Deletions are marked by dotted lines. (B) Representative I_Ca (red) and I_Ba (black) through 1.2-C+ICDI1.4. (C) Voltage-dependence of f for 1.2-C+ICDI1.4. (D and E) Representative I_Ca and I_Ba through 1.2ΔC-ICDI1.4 (D) and 1.2-A+ICDI1.4 (E). (F) f_max values for channels are shown in A.