Figure 2.

Effects of adiponectin treatment on food intake, body weight gains, and circulating levels of glucose and insulin. (a) Serum adiponectin levels in mice fed with LC diet, LE diet, or LE diet plus adiponectin infusion (LE + Ad), as described in the text (n = 5). Serum samples were collected at different times following adiponectin treatment. (b) Food intake in LE diet mice treated with or without adiponectin (n = 6). (c) Average daily body weight gains over 2 weeks of adiponectin treatment (n = 6). (d) Fasting glucose levels over adiponectin treatment period (n = 6). (e) Fasting plasma insulin levels over adiponectin treatment period (n = 6). Note that adiponectin and alcohol treatment also have no obvious effects on plasma levels of insulin and glucose in the fed state (data not shown). *P < 0.001 for adiponectin-treated group versus other two groups.