Table 1.

Elevation of serum immunoglobulin levels in TALL-1 transgenic mice

	IgM (μg/m)	IgA (μg/ml)	IgE (ng/ml)	IgG1 (μg/m)	IgG2a (μg/ml)	IgG2b (μg/ml)	IgG3 (μg/ml)
TALL-1	7,640  ± 742	11,360  ± 3,045	634  ± 77	396  ± 53	1,132  ± 109	1,002  ± 190	1,528  ± 358
Control	475  ± 48	85  ± 17	359  ± 71	198  ± 40	302  ± 100	248  ± 51	115  ± 41

Control mice (n = 5) and TALL-1 transgenic mice (n = 5) were bled at 8 wks of age. Serum IgM, IgA, IgE, and IgG subclasses were quantitated by ELISA. Values represent mean ± SEM. All TALL-1 immunoglobulin levels were significantly increased (Student's t test; P < 0.05 as compared to the control groups).