Table 1.
Specificity | Donor | Vaccinea | #Fabsb | Insertionsc | Deletionsc |
PPS 23F | 002 | conjugate | 3 | 0 | 0 |
008 | conjugate | 10 | 1 | 0 | |
014 | conjugate | 3 | 0 | 0 | |
018 | PPS | 3 | 1 | 0 | |
023 | PPS | 3 | 0 | 0 | |
025 | PPS | 6 | 0 | 0 | |
027 | PPS | 4 | 1 | 0 | |
PPS 6B | 001 | conjugate | 1 | 0 | 0 |
002 | conjugate | 5 | 0 | 0 | |
003 | conjugate | 11 | 9 | 0 | |
010 | conjugate | 11 | 0 | 1 | |
011 | conjugate | 20 | 0 | 0 | |
023 | PPS | 9 | 1 | 1 | |
PPS 14 | 011 | conjugate | 4 | 1 | 1 |
012 | conjugate | 23 | 0 | 0 | |
023 | PPS | 9 | 0 | 4 | |
PA | 001 | AVA | 32 | 0 | 1 |
aVaccine; PPS (23-valent pneumococcal polysaccharide vaccine), conjugate (pneumococcal polysaccharides conjugate to CRM197) or AVA (anthrax vaccine). bNumber of antigen-specific Fabs isolated from this donor. cNumber of Fabs isolated with codon insertions and/or deletions.