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Effect of dietary cholesterol on liver HMGR and cholesterol 7α hydroxylase activities in WT and apoE knockout mice: WT (E+/+) and apoE knockout (E−/−) animals were fed with either 0.02% (open bars) or 0.5% cholesterol (filled bars), livers were harvested, and HMGR and cholesterol 7α hydroxylase activities were measured as described in Experimental Procedures. Data displayed are the mean ± SD of five animals in each group.
