Table 3.
Region of amplification | Population | 5-year M FS [95% CI] | Hazard ratio [95% CI] | p-value | |||
W hole | N + | N - | With amplification | Without amplification | |||
8p12 | + | 68.75 [56.73–83.3] | 82.4 [76.6–88.7] | 2.25 [1.28–3.93] | 0.0046 | ||
8p12 | + | 63.2 [46.6–85.6] | 72.6 [63–83.67] | 1.87 [0.95–3.71] | 0.071 | ||
8p12 | + | 73.77 [57.59–94.49] | 91.33 [85.37–97.70] | 2.98 [1.1–8.06] | 0.031 | ||
8q24 | + | 78.6 [59.8–100] | 82.61 [77.63–87.92] | 0.825 [0.25–2.75] | 0.75 | ||
8q24 | + | 75 [50.3–100] | 74.53 [66.32–83.75] | 0.728 [0.17–3.04] | 0.66 | ||
8q24 | + | 83.3 [58.3–100] | 89.55 [84.09–95.36] | 0.825 [0.09–7.66] | 0.87 | ||
11q13 | + | 75.93 [65.28–88.31] | 83.95 [79.18–89] | 1.46 [0.8–2.67] | 0.22 | ||
11q13 | + | 75.72 [61.54–93.17] | 74 [65.7–83.4] | 0.962 [0.44–2.1] | 0.92 | ||
11q13 | + | 76.02 [60.88–94.92] | 91.72 [86.91–96.80] | 2.46 [0.93–6.48] | 0.069 | ||
12p13 | + | 91.67 [77.29–100] | 82.23 [77.85–86.85] | 0.427 [0.06–3.08] | 0.4 | ||
12p13 | + | 100 [100-100] | 72.14 [64.84–80.26] | * | 1 | ||
12p13 | + | 83.3 [58.3–100] | 91.28 [86.85–95.94] | 2.46 [0.32–18.75] | 0.39 | ||
17q12 | + | 64.7 [47.5–88.2] | 83.92 [79.28–88.83] | 2.09 [1.02–4.26] | 0.044 | ||
17q12 | + | 68.2 [48.6–95.7] | 75.37 [67.54–84.10] | 1.24 [0.52–2.95] | 0.63 | ||
17q12 | + | 55.6 [27.4–100] | 91.25 [86.44–96.33] | 4.2 [1.18–14.95] | 0.027 | ||
20q13Z | + | 85.4 [71.27–100] | 79.43 [73.82–85.47] | 0.57 [0.18–1.83] | 0.35 | ||
20q13Z | + | 90.91 [75.41–100] | 63.98 [54.65–74.89] | 0.186 [0.03–1.35] | 0.097 | ||
20q13Z | + | 79.5 [57.7–100] | 93.05 [88.18–98.19] | 2.58 [0.55–12.15] | 0.23 | ||
20q13Co | + | 90.43 [78.63–100] | 79.80 [74.71–85.24] | 0.364 [0.09–1.51] | 0.16 | ||
20q13Co | + | 87.84 [73.37–100] | 66.80 [58.20–76.66] | 0.276 [0.07–1.15] | 0.076 | ||
20q13Co | + | 100 [100-100] | 90.40 [85.35–95.75] | * | 1 |
*No event in the amplified group