Figure 2.
Desmoid fibromas develop on the abdominal body wall of ApcMin/+ p53−/− mice. The abdominal body wall was isolated and fixed in 10% formalin. The postfixed tissue was either stained with Fast green (A) or further dissected to isolate individual tumors. Isolated tumors were sectioned and stained either with Masson's Trichrome (B and C), in which muscle stains red and collagen blue, or with hematoxylin and eosin (D and E). These lesions can form on the surface of the abdominal wall muscle (B and D) or infiltrate and disrupt the organization of this tissue (C and E). The scale bar in A represents 5 mm, whereas that in B represents 0.5 mm. The magnification in B–E was the same.