Table 4.
Individual study weighting validation with data set 1
| Weighting method and weights (%) | ||||||||
| IV | MH | PETO | IV+t | |||||
| Studies | MIX | STATA | MIX | STATA | MIX | STATA | MIX | STATA |
| Fletcher | 0.07% | 0.07% | 0.18% | 0.18% | 0.11% | 0.11% | 0.21% | 0.21% |
| Dewar | 0.21% | 0.21% | 0.27% | 0.27% | 0.22% | 0.22% | 0.59% | 0.59% |
| Euro 1 | 0.74% | 0.74% | 0.53% | 0.53% | 0.74% | 0.74% | 1.99% | 1.99% |
| Euro 2 | 3.38% | 3.38% | 3.68% | 3.68% | 3.39% | 3.39% | 7.18% | 7.18% |
| Heikinheimo | 0.95% | 0.95% | 0.74% | 0.74% | 0.95% | 0.95% | 2.50% | 2.50% |
| Italian | 0.89% | 0.89% | 0.76% | 0.76% | 0.88% | 0.88% | 2.35% | 2.35% |
| Australia 1 | 1.39% | 1.39% | 1.39% | 1.39% | 1.38% | 1.38% | 3.50% | 3.50% |
| Frankfurt | 0.80% | 0.80% | 1.18% | 1.18% | 0.90% | 0.90% | 2.14% | 2.14% |
| NHLBI-SMIT | 0.21% | 0.21% | 0.12% | 0.12% | 0.24% | 0.24% | 0.60% | 0.60% |
| Frank | 0.29% | 0.29% | 0.26% | 0.26% | 0.29% | 0.29% | 0.82% | 0.82% |
| Valere | 0.42% | 0.42% | 0.35% | 0.35% | 0.42% | 0.42% | 1.17% | 1.17% |
| Klein | 0.07% | 0.07% | 0.04% | 0.04% | 0.10% | 0.10% | 0.21% | 0.21% |
| UK-Collab | 1.85% | 1.85% | 1.67% | 1.67% | 1.81% | 1.81% | 4.46% | 4.46% |
| Austrian | 2.23% | 2.23% | 2.64% | 2.64% | 2.34% | 2.34% | 5.21% | 5.21% |
| Australia 2 | 1.14% | 1.14% | 1.24% | 1.24% | 1.13% | 1.13% | 2.94% | 2.94% |
| Lasierra | 0.07% | 0.07% | 0.14% | 0.14% | 0.09% | 0.09% | 0.20% | 0.20% |
| N Ger Collab | 2.35% | 2.35% | 1.85% | 1.85% | 2.33% | 2.33% | 5.44% | 5.44% |
| Witchitz | 0.22% | 0.22% | 0.22% | 0.22% | 0.22% | 0.22% | 0.64% | 0.64% |
| Euro 3 | 1.05% | 1.05% | 1.24% | 1.24% | 1.09% | 1.09% | 2.73% | 2.73% |
| ISAM | 2.96% | 2.96% | 2.74% | 2.74% | 2.92% | 2.92% | 6.50% | 6.50% |
| GISSI-1 | 33.05% | 33.05% | 31.84% | 31.84% | 32.65% | 32.65% | 21.00% | 21.00% |
| Olson | 0.07% | 0.07% | 0.10% | 0.10% | 0.08% | 0.08% | 0.20% | 0.20% |
| Baroffio | 0.05% | 0.05% | 0.30% | 0.30% | 0.15% | 0.15% | 0.14% | 0.14% |
| Schreiber | 0.08% | 0.08% | 0.13% | 0.13% | 0.10% | 0.10% | 0.22% | 0.22% |
| Cribier | 0.05% | 0.05% | 0.04% | 0.04% | 0.05% | 0.05% | 0.15% | 0.15% |
| Sainsous | 0.20% | 0.20% | 0.26% | 0.26% | 0.22% | 0.22% | 0.57% | 0.57% |
| Durand | 0.17% | 0.17% | 0.19% | 0.19% | 0.17% | 0.17% | 0.47% | 0.47% |
| White | 0.18% | 0.18% | 0.54% | 0.54% | 0.35% | 0.35% | 0.51% | 0.51% |
| Bassand | 0.25% | 0.25% | 0.30% | 0.30% | 0.27% | 0.27% | 0.71% | 0.71% |
| Vlay | 0.06% | 0.06% | 0.09% | 0.09% | 0.07% | 0.07% | 0.19% | 0.19% |
| Kennedy | 0.71% | 0.71% | 0.78% | 0.78% | 0.71% | 0.71% | 1.90% | 1.90% |
| ISIS-2 | 43.68% | 43.68% | 43.92% | 43.92% | 43.47% | 43.47% | 22.18% | 22.18% |
| Wisenberg | 0.14% | 0.14% | 0.28% | 0.28% | 0.16% | 0.16% | 0.40% | 0.40% |
In a meta-analysis, each study is given a weight that determines its influence on the overall result and this weight depends on the weighting method. Proper weighting is crucial to get correct results, so we validated all individual study weights for each data set and weighting method. The table shows the odds ratio weighting validation for data set 1. Abbreviations: "IV" = inverse variance weighting, "MH" = Mantel-Haenszel weighting, "PETO" = Peto weighting, and "IV+t" = inverse variance plus tau, which refers to random effects weighting according to the DerSimonian-Laird method.