Table 3.
Codon 10 genotype | TGF-β1 mRNA/GAPDH mRNA, mean ± SEM | P |
---|---|---|
C/C + T/C | 5.06 ± 0.30 | |
T/T | 3.53 ± 0.46 | 0.0074 |
TGF-β1 mRNA levels and GAPDH mRNA levels were quantified by using gene-specific competitor constructs in competitive PCR and correlated with codon 10 genotype. mRNA steady-state levels (log-transformed) are from 87 individuals (34 white hypertensives, 16 black hypertensives, 26 white normotensives, and 11 black normotensives), who also were genotypes for codon 10. P value for the F statistic of a one-way ANOVA is shown.