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. Author manuscript; available in PMC: 2007 Nov 1.
Published in final edited form as: J Nutr. 2006 Nov;136(11):2735–2742. doi: 10.1093/jn/136.11.2735

FIGURE 1.

FIGURE 1

Holocarboxylase synthetase (HCS) binds to distinct chromosomal sites in wild-type Drosophila melanogaster. Panel A: Immunostaining of fixed polytene chromosomes with anti-HCS serum. Panel B: Phase contrast image of chromosomes in A. Panel C: Immunostaining of fixed polytene chromosomes with pre-immune serum. Panel D: Phase contrast image of chromosomes in C. Legend: filled arrowheads = puffs that stain for HCS; open arrowheads = puffs that do not stain for HCS; line = non-puffed site that stains for HCS; t = staining telomere; N = nucleolus; cc = heterochromatic chromocenter; X = X chromosome; 2L and 2R = left and right arms of chromosome 2; 3L and 3R = left and right arms of chromosome 3.