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RNAi knockdown of HCS and BTD is associated with decreased biotinylation of histones in Drosophila melanogaster. Panel A: Abundance of biotinylated histones in HCS-RNAi and BTD-RNAi flies compared with Act5C-Gal4 control flies, as judged by streptavidin blotting. Panel B: Transblots probed with anti-K9BioH3. Panel C: Transblots probed with anti-K18BioH3. Note that all lanes shown were from the same blot, although the order presented is changed in order to facilitate comparisons.
