TABLE 1.
Select clusters of genes with increased or decreased expression in male HCS-deficient (HCS-RNAi) Drosophila compared with Act5C-Gal4 control flies
| Expression (HCS-RNAi vs. Act5C-Gal4)
|
||
|---|---|---|
| Gene Ontology category | Increased | Decreased |
| Biological process | ||
| Signal transduction | 7 | 1 |
| Cell cycle | 2 | 0 |
| Cell organization | 3 | 0 |
| Cell death | 3 | 1 |
| Catabolism | 6 | 2 |
| Defense response | 2 | 10 |
| Transport | 15 | 2 |
| Nucleic acid metabolism | 2 | 0 |
| Regulation of transcription | 14 | 2 |
| Proteolysis and peptidolysis | 18 | 6 |
| Morphogenesis | 5 | 1 |
| Molecular function | ||
| Protein binding | 7 | 0 |
| DNA/nucleotide binding | 18 | 1 |
| Transcription factor binding | 8 | 1 |
| Kinase | 12 | 4 |
| Transferase | 3 | 10 |