Abstract
Airways obstruction was measured before and after inhaled ipratropium bromide in 32 wheezy children aged between 3 months and 2 years 8 months using a total body plethysmograph and a modification of the forced oscillation technique. No relationship was found between age and incidence of response. About 40% of those under age 18 months had an improvement in lung function. This form of treatment may have a place in the management of the wheezy infant too young to respond to beta-2 stimulants.
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Selected References
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- Cogswell J. J. Forced oscillation technique for determination of resistance to breathing in children. Arch Dis Child. 1973 Apr;48(4):259–266. doi: 10.1136/adc.48.4.259. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Doershuk C. F., Downs T. D., Matthews L. W., Lough M. D. A method for ventilatory measurements in subjects 1 month--5 years of age: Normal results and observations in disease. Pediatr Res. 1970 Mar;4(2):165–174. doi: 10.1203/00006450-197003000-00007. [DOI] [PubMed] [Google Scholar]
- Groggins R. C., Milner A. D., Stokes G. M. Bronchodilator effects of clemastine, ipratropium, bromide, and salbutamol in preschool children with asthma. Arch Dis Child. 1981 May;56(5):342–344. doi: 10.1136/adc.56.5.342. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lenney W., Milner A. D. Alpha and beta adrenergic stimulants in bronchiolitis and wheezy bronchitis in children under 18 months of age. Arch Dis Child. 1978 Sep;53(9):707–709. doi: 10.1136/adc.53.9.707. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lenney W., Milner A. D. At what age do bronchodilator drugs work? Arch Dis Child. 1978 Jul;53(7):532–535. doi: 10.1136/adc.53.7.532. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rutter N., Milner A. D., Hiller E. J. Effect of bronchodilators on respiratory resistance in infants and young children with bronchiolitis and wheezy bronchitis. Arch Dis Child. 1975 Sep;50(9):719–722. doi: 10.1136/adc.50.9.719. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stocks J., Levy N. M., Godfrey S. A new apparatus for the accurate measurement of airway resistance in infancy. J Appl Physiol Respir Environ Exerc Physiol. 1977 Jul;43(1):155–159. doi: 10.1152/jappl.1977.43.1.155. [DOI] [PubMed] [Google Scholar]