Table 1.
Reln-expressing neurons in three cortical areas of nonhuman primates
| Patas (neurons per mm3 × 103)
|
Macaque (neurons per mm3 × 103)
|
Baboon (neurons per mm3 × 103)
|
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| PFC | CingC | VC | PFC | CingC | VC | PFC | CingC | VC | ||
| I | RELN | 7.8 ± 0.73 | 9.7 ± 0.87 | 5.0 ± 0.66 | 5.9 ± 0.45 | 8.1 ± 1.13 | 7.5 ± 0.47 | 6.3 ± 0.39 | 9.1 ± 0.81 | 7.5 ± 0.45 |
| NeuN | 22.8 ± 2.61 | 15.3 ± 1.67 | 6.6 ± 0.92 | 20.0 ± 1.16 | 9.4 ± 1.40 | 10.6 ± 0.78 | 15.3 ± 104 | 13.3 ± 1.22 | 5.5 ± 0.61 | |
| % | (34.2) | (63.3) | (75.8) | (30.0) | (86.7) | (70.6) | (41.2) | (68.2) | (100) | |
| II | RELN | 2.8 ± 0.31 | 2.5 ± 0.66 | 2.5 ± 0.66 | 2.8 ± 0.31 | 2.5 ± 0.47 | 1.9 ± 0.62 | 3.3 ± 0.29 | 3.9 ± 0.50 | 3.1 ± 0.48 |
| NeuN | 72.8 ± 2.81 | 54.1 ± 3.13 | 113.4 ± 3.98 | 56.8 ± 1.66 | 53.4 ± 2.3 | 145.6 ± 5.53 | 49.1 ± 1.85 | 64.5 ± 1.42 | 88.4 ± 3.95 | |
| % | (3.9) | (4.6) | (2.2) | (5.0) | (4.7) | (1.3) | (6.7) | (6.1) | (3.5) | |
| III | RELN | 0.62 ± 0.40 | 1.3 ± 0.66 | 0.3 ± 0.31 | 1.3 ± 0.47 | 1.6 ± 0.45 | 0.62 ± 0.40 | 1.71 ± 0.37 | 1.1 ± 0.39 | 0.93 ± 0.31 |
| NeuN | 55.6 ± 3.95 | 41.6 ± 1.57 | 101.3 ± 3.47 | 42.5 ± 0.95 | 37.2 ± 1.80 | 87.5 ± 4.91 | 32.0 ± 2.02 | 39.1 ± 1.42 | 84.1 ± 2.26 | |
| % | (1.1) | (3.0) | (0.3) | (2.9) | (4.2) | (0.7) | (5.4) | (2.8) | (1.1) | |
| IV | RELN | 0.31 ± 0.31 | 0 | 0 | 0.31 ± 0.31 | 0 | 0.31 ± 0.31 | 1.3 ± 0.51 | 0.15 ± 0.15 | 0.15 ± 0.15 |
| NeuN | 69.1 ± 4.41 | 24.7 ± 2.73 | 1.20 ± 5.41 | 63.8 ± 4.48 | 33.1 ± 2.98 | 114.4 ± 6.14 | 58.6 ± 2.04 | 35.5 ± 1.65 | 86.6 ± 2.40 | |
| % | (0.5) | (0) | (0) | (0.5) | (0) | (0.3) | (2.1) | (0.5) | (0.2) | |
| V | RELN | 0.31 ± 0.31 | 0 | 0 | 0 | 0 | 0 | 0.31 ± 0.21 | 0 | 0 |
| NeuN | 63.4 ± 5.30 | 42.2 ± 2.08 | 103.4 ± 5.87 | 46.6 ± 2.83 | 50.3 ± 3.58 | 81.9 ± 3.65 | 42.2 ± 1.98 | 64.7 ± 2.82 | 81.6 ± 3.78 | |
| % | (0.4) | (0) | (0) | (0) | (0) | (0) | (0.7) | (0) | (0) | |
| VI | RELN | 0 | 0 | 0 | 0 | 0 | 0 | 0.31 ± 0.21 | 0 | 0 |
| NeuN | 47.5 ± 1.77 | 42.8 ± 2.29 | 127.5 ± 4.23 | 42.2 ± 2.85 | 37.8 ± 2.19 | 101.2 ± 5.26 | 33.8 ± 1.72 | 38.1 ± 10.5 | 66.1 ± 2.48 | |
| % | (0) | (0) | (0) | (0) | (0) | (0) | (0.9) | (0) | (0) | |
Mean ± SEM number of Reln-expressing neurons (first row; bold), mean ± SEM number of NeuN-positive neurons (middle row), and percentage of Reln-expressing neurons (in parentheses) relative to the total number of neurons in cortical layers I–VI of prefrontal cortex (PFC), anterior cingulate cortex (CingC), and visual cortex (VC) of the patas monkey, macaque, and baboon. For definition of the area see Materials and Methods. RELN, Reln-expressing neurons; NeuN, NeuN-positive cells; %, Reln-expressing neurons/NeuN-positive cells.